5-Amino-1MQ 5 mg

ニコチンアミド N-メチルトランスフェラーゼ（NNMT）の選択的阻害薬。細胞代謝、脂質蓄積、脂肪組織生物学への影響が研究モデルで検討されています。

5-Amino-1MQ (5-amino-1-methylquinolinium) is a small-molecule research compound (not a peptide) that acts as an inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT). NNMT is studied as a regulator of cellular NAD+/methyl-donor balance, with downstream implications for adipocyte function and metabolic flexibility. Quantum Labs supplies 5-Amino-1MQ for Australian research applications.

Research on NNMT inhibition has expanded substantially over the past decade as the enzyme's role in metabolism has been characterised. 5-Amino-1MQ is one of the most studied selective NNMT inhibitors and is used as a research tool to probe NNMT-dependent pathways. Material is HPLC-verified and ships from Australian stock; supplied for laboratory research use only.

作用機序

研究では、NNMT の阻害が細胞内 NAD+ と SAM の利用能を高め、研究対象の代謝および脂肪形成マーカーに下流効果をもたらすことが示唆されています。