TB-500
Actin-binding research peptide
Buy TB-500 in Australia for actin-binding research. Lab-verified, lyophilised, Australian-shipped.
Research Use Only. This compound is sold strictly for in-vitro research and laboratory purposes and is not intended for human consumption or therapeutic use. By purchasing you confirm you are a qualified researcher and agree to our full disclaimer.
Thymosin Beta-4 fragment studied for its role in cell migration, actin regulation, and tissue remodelling in research applications.
TB-500 is a synthetic peptide fragment of the naturally occurring protein thymosin β-4. The molecule contains the active actin-binding domain of full-length thymosin β-4 and has been extensively studied for its role in cell migration, wound-healing models, and tissue regeneration pathways. Quantum Labs supplies TB-500 as a lyophilised powder in sealed vials for Australian research applications.
TB-500 is most often studied alongside BPC-157 in tissue-repair research, where the two compounds target complementary mechanisms — BPC-157 acting predominantly through nitric oxide and VEGF pathways, TB-500 acting on actin sequestration and cytoskeletal remodelling. Our BPC-157 + TB-500 research stack supplies both compounds in pre-portioned vials.
Material ships from Australian stock, HPLC-verified to ≥99% purity with batch-level certificates of analysis available on request.
Research Mechanism
Studied for binding to G-actin and influencing cell migration markers. Research suggests potential benefits for tissue repair pathways.
HPLC verified against a ≥99% purity specification. Independently tested by accredited third-party laboratories.
Mechanism in research literature
TB-500 contains the LKKTETQ actin-binding sequence from thymosin β-4. In research models, this peptide region has been shown to modulate actin polymerisation, promote endothelial cell migration, and influence the differentiation of mesenchymal stem cells toward repair phenotypes. The full mechanism is still under investigation in pre-clinical literature.
TB-500 — frequently asked questions
What is TB-500?
TB-500 is a synthetic fragment of the naturally occurring protein thymosin β-4, containing the active actin-binding domain. It is supplied for laboratory research into cell-migration and tissue-repair pathways.
Is TB-500 legal in Australia?
TB-500 is restricted for compounded human therapeutic supply in Australia. Research-grade TB-500 supplied without therapeutic representation remains available for laboratory use. Quantum Labs supplies TB-500 for research use only.
What is the typical TB-500 research dosage?
Published animal studies have used TB-500 doses in the 2-10 mg/kg range for systemic models. Human therapeutic dosing is not established. Researchers should reference primary literature for protocol-specific dosing.
Can TB-500 be used with BPC-157?
Combined BPC-157 + TB-500 protocols are common in tissue-repair research. The two compounds are believed to act on complementary pathways — BPC-157 on nitric oxide and VEGF, TB-500 on actin and cell migration. Quantum Labs supplies a BPC-157 + TB-500 research stack in pre-portioned vials.
What's the difference between TB-500 and thymosin β-4?
Full-length thymosin β-4 is a 43-amino-acid endogenous protein. TB-500 is the shorter active fragment containing the LKKTETQ actin-binding sequence. The shorter fragment is more practical for research-grade synthesis and is the form most studied in pre-clinical tissue-repair literature.
How is TB-500 stored?
Lyophilised TB-500 is stable at 2-8°C in unopened sealed vials. Once reconstituted, the working solution is typically stored at 2-8°C and used within 30 days. Avoid freeze-thaw cycles.
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